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Thy1/CD90; Claim to fame:: Smallest and one of the most conserved members of the immunoglobulin family; Lead to the discovery and characterization of GPI anchor
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Implications in disease. Oct-4 has been implicated in tumorigenesis of adult germ cells. Ectopic expression of the factor in adult mice has been found to cause the formation of dysplastic lesions of the skin and intestine.
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